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Group leader: Martin Schalling (co-supervisor), Martin Ingvar (co-supervisor), Arne Öhman
E-mail: tina.lonsdorf@ki.se
Tina Lonsdorf
Position: PhD studentGroup leader: Martin Schalling (co-supervisor), Martin Ingvar (co-supervisor), Arne Öhman
E-mail: tina.lonsdorf@ki.se
Summary of ongoing research projects:
- Genetic gating of human fear learning and extinction (both behavioural studies and fMRI studies)
- Emotion regulation and genetic polymorphisms
- The impact of genetic polymorphisms on the symptomatic profile and outcome of cognitive behavioural treatment in panic patients (Collaboration with Nils Lindefors/Christian Rueck, KI Huddinge)
- Genetic polymorphisms and personality
Methods: SNP genotyping, VNTR genotyping, fMRI, psychophysiology
Selected Publications:
Kirsch P, Reuter M, Mier D, Lonsdorf T, Stark R, Gallhofer B, Vaitl D, Hennig J. Imaging gene-substance interactions: the effect of the DRD2 TaqIA polymorphism and the dopamine agonist bromocriptine on the brain activation during the anticipation of reward. Neurosci. Lett. 405, 196-201 (2006). PubMed
Lonsdorf TB, Rück C, Bergström J, Andersson G, Ohman A, Schalling M, Lindefors N. The symptomatic profile of panic disorder is shaped by the 5-HTTLPR polymorphism. Prog. Neuropsychopharmacol. Biol. Psychiatry , (2009). PubMed
Lonsdorf TB, Weike AI, Nikamo P, Schalling M, Hamm AO, Ohman A. Genetic gating of human fear learning and extinction: possible implications for gene-environment interaction in anxiety disorder. 20, 198-206 (2009). PubMed
Jensen KB, Lonsdorf TB, Schalling M, Kosek E, Ingvar M. Increased sensitivity to thermal pain following a single opiate dose is influenced by the COMT val(158)met polymorphism. PLoS ONE 4, e6016 (2009). PubMed
Kosek E, Jensen KB, Lonsdorf TB, Schalling M, Ingvar M. Genetic variation in the serotonin transporter gene (5-HTTLPR, rs25531) influences the analgesic response to the short acting opioid Remifentanil in humans. 5, 37 (2009). PubMed
Lonsdorf TB, Rück C, Bergström J, Andersson G, Ohman A, Schalling M, Lindefors N. The symptomatic profile of panic disorder is shaped by the 5-HTTLPR polymorphism. Prog. Neuropsychopharmacol. Biol. Psychiatry , (2009). PubMed
Lonsdorf TB, Weike AI, Nikamo P, Schalling M, Hamm AO, Ohman A. Genetic gating of human fear learning and extinction: possible implications for gene-environment interaction in anxiety disorder. 20, 198-206 (2009). PubMed
Jensen KB, Lonsdorf TB, Schalling M, Kosek E, Ingvar M. Increased sensitivity to thermal pain following a single opiate dose is influenced by the COMT val(158)met polymorphism. PLoS ONE 4, e6016 (2009). PubMed
Kosek E, Jensen KB, Lonsdorf TB, Schalling M, Ingvar M. Genetic variation in the serotonin transporter gene (5-HTTLPR, rs25531) influences the analgesic response to the short acting opioid Remifentanil in humans. 5, 37 (2009). PubMed
Lonsdorf, T.B., Weike, A.I., Golkar, A., Schalling, M., Hamm, A. & Öhman, A. (2010). Amygdala-dependent fear conditioning in humans is modulated by the BDNFval66met polymorphism. Behavioral Neuroscience, 124(1):9-15